LYMPHATIC SURGERY

Discover FLUOBEAM® LM

METHODOLOGICAL APPROACH AND OPERATING STRATEGY WITH FLUOBEAM® LM?

After an interstitial injection, indocyanine green (ICG) is drained to the nearest lymph node chain. In lymphatic surgery, ICG fluorescence allows to visualize the superficial drainage and to identify the areas where functional lymphatic vessels and blockages are located. This allows a good understanding A good evaluation of the disease’s progression and to eventually plan a surgery in which fluorescence will help identify the critical areas where to perform lymphatic-venous anastomoses.
Another application of fluorescence in lymphatic drainage is the identification of sentinel lymph nodes in cancer surgery.. In axillary lymph node biopsy, this technique should benefit patients who do not have access to isotope detection. This technique can also be used in reverse mapping when we want to remove nodes and preserve those that drain nearby areas.

Fluobeam® LM in action

Observation of lymphatic vessels

In consultation, FLUOBEAM® LM can be used for real-time imaging of functional superficial lymphatic vessels. It helps in the early diagnosis of lymphedema, in the choice of treatment (surgical or medical), and in the postoperative follow-up.

In surgery, FLUOBEAM® LM can be used to identify before and during surgery the functional lymphatic vessels that will be used for a lymphatic-venous anastomosis (LVA). In addition, FLUOBEAM can be used in “reverse mapping” to map and preserve lymphatic drainage during lymph node surgery and can also be used for postoperative follow-up.

Observation of lymphatic vessels

In consultation, FLUOBEAM® LM can be used for real-time imaging of functional superficial lymphatic vessels. It helps in the early diagnosis of lymphedema, in the choice of treatment (surgical or medical), and in the postoperative follow-up.

In surgery, FLUOBEAM® LM can be used to identify before and during surgery the functional lymphatic vessels that will be used for a lymphatic-venous anastomosis (LVA). In addition, FLUOBEAM can be used in “reverse mapping” to map and preserve lymphatic drainage during lymph node surgery and can also be used for postoperative follow-up.

Sentinel node biopsy

The sentinel lymph node is the first lymph node where cancer cells are most likely to migrate from the primary tumor. The sentinel node technique involves detecting this node, removing it and having it analyzed.

Fluorescence imaging and Indocyanine Green have been recently introduced in the clinic as an alternative for surgical guidance. FLUOBEAM® LM allows visualization of superficial lymphatic drainage and detection of the sentinel lymph node after incision, for different tumor types.

Sentinel node biopsy

The sentinel lymph node is the first lymph node where cancer cells are most likely to migrate from the primary tumor. The sentinel node technique involves detecting this node, removing it and having it analyzed.

Fluorescence imaging and Indocyanine Green have been recently introduced in the clinic as an alternative for surgical guidance. FLUOBEAM® LM allows visualization of superficial lymphatic drainage and detection of the sentinel lymph node after incision, for different tumor types.

TESTIMONIALS

"Indocyanine green can be used in sentinel node detection in early breast cancers. It is an accurate, safe and inexpensive technique."

Dr Charlotte NGO

Dr Charlotte NGO

Gynecological and breast cancer surgery, Geaorges Pompidou European Hospital, Paris, France

"It is essential to understand lymphedema works so FLUOBEAM® is really important for this kind of indication. I can't do lymphatic surgery without fluorescence imaging."

Pr Jaune MASIA

Pr Jaune MASIA

Plastic and Aesthetic Surgery, Hospital de la Santé Creu i Sant Pau, Barcelona, Spain

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PUBLICATIONS
Gray RJ. et al. Features of lymphatic dysfunction in compressed skin tissues – Implications in pressure ulcer aetiology. J Tissue Viability 2016
Gray RJ. et al. Monitoring contractile dermal lymphatic activity following uniaxial mechanical loading. Medical Engineering and Physics 2016
Miranda Garcés M. et al. Intratissue lymphovenous communications in the mechanism of action of vascularized lymph node transfer. J Surg Oncol. 2016
Lopera C. et al. Investigating the Short-Term Effects of Manual Lymphatic Drainage and Compression Garment Therapies on Lymphatic Function Using Near-Infrared Imaging. Lymphat Res Biol. 2017
Stoffels I. et al. Evaluation of a radioactive and fluorescent hybrid tracer for sentinel lymph node biopsy in head and neck malignancies: prospective randomized clinical trial to compare ICG-(99m)Tc-nanocolloid hybrid tracer versus (99m)Tc-nanocolloid. Eur J Nucl Med Mol Imaging 2015
Stoffels I. et al. Intraoperative Fluorescence Imaging for Sentinel Lymph Node Detection: Prospective Clinical Trial to Compare the Usefulness of Indocyanine Green vs Technetium Tc 99m for Identification of Sentinel Lymph Nodes. JAMA Surg. 2015
Markuszewski M. et al. Comparison of Real-Time Fluorescent Indocyanine Green and (99m)Tc-Nanocolloid Radiotracer Navigation in Sentinel Lymph Node Biopsy of Penile Cancer. Clin Genitourin Cancer 2015
Polom W. et al. Fluorescent versus radioguided lymph node mapping in bladder cancer. Genitourinary Cancer 2016
Christensen A. et al. Feasibility of Real-Time Near-Infrared Fluorescence Tracer Imaging in Sentinel Node Biopsy for Oral Cavity Cancer Patients. Ann Surg Oncol. 2016
Nguyen D.P. et al. A Specific Mapping Study Using Fluorescence Sentinel Lymph Node Detection in Patients with Intermediate- and High-risk Prostate Cancer Undergoing Extended Pelvic Lymph Node Dissection. Eur Urol. 2016

FLUOBEAM® LM is indicated to visualize on a screen the flow, the distribution and/or the accumulation of Indocyanine green (ICG) before, during and after surgery for the indications such as: visualization of the blood flow, visualization of the lymphatic flow, visualization and identification of the bile ducts during hepatobiliary surgery, visualization and detection of primary liver tumors and/or hepatic metastases.FLUOBEAM® LM is also indicated to facilitate the visualization of parathyroid glands by auto-fluorescence (natural fluorescence without ICG injection) during thyroid and parathyroid surgeries. This is a class IIa medical device, CE017. Product manufactured by FLUOPTICS SAS, France. For proper use, please read carefully all instructions in the specific instructions for use for each product.

Warning

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